He observed that when chickens were fed the native diet of white rice, they developed the symptoms of beriberi, but when they were fed unprocessed brown rice with the outer bran intact, there were no symptoms of the disease. When Eijkman fed brown rice to beriberi patients, they were cured.
What is the problem that Dr Eijkman investigated?
In 1887 a strange nerve disease attacked the people in the Dutch East Indies. The disease was beriberi. Symptoms of the disease included weakness and loss of appetite, victims often died of heart failure. Scientists thought the disease might be caused by bacteria.
What was the hypothesis in the beriberi experiment?
In the culture dishes without the mold, no clear areas were present. Fleming hypothesized that the mold must be producing a chemical that killed the bacteria. He decided to isolate this substance and test it to see if it would kill bacteria. Fleming transferred the mold to a nutrient broth solution.
Did Dr Eijkman data support his original hypothesis?
Eijkman rejected the original hypothesis because the chickens diet was changed from whole-grain rice to polished rice. Dr. Eijkman found out that the polished rice lacks thiamine. In 1887 a strange nerve disease, called beriberi, attacked the people in the Dutch East Indies.
Why did Eijkman begin by looking for microorganisms as a cause of beriberi?
Eijkman surmised that polished rice lacked a dietary component found in unpolished rice, and that beriberi was caused by depriving the body of this component, which he called “the anti-beriberi factor”.
What was Dr Eijkman hypothesis?
Eijkman believed that the polyneuritis was caused by a toxic chemical agent, possibly originating from the action of intestinal microorganisms on boiled rice.
What causes beriberi?
Beriberi is a disease caused by a vitamin B-1 deficiency, also known as thiamine deficiency. There are two types of the disease: wet beriberi and dry beriberi. Wet beriberi affects the heart and circulatory system.
What is the original hypothesis?
A scientific hypothesis is the initial building block in the scientific method. Many describe it as an “educated guess,” based on prior knowledge and observation. A hypothesis also includes an explanation of why the guess may be correct, according to National Science Teachers Association.
Who discovered beriberi?
In the late 1800s, Christiaan Eijkman was sent to the Dutch Indies to study the cause of beriberi, a severe polyneuritis affecting residents of Java.
What is the scientific method worksheet?
The scientific method is a process that scientists use to better understand the world around them. It includes making observations and asking a question, forming a hypothesis, designing an experiment, collecting and analyzing data, and drawing a conclusion. This is sometimes also referred to as scientific inquiry.
What medical advancement did penicillin lead to?
In 1928, at St. Mary’s Hospital, London, Alexander Fleming discovered penicillin. This discovery led to the introduction of antibiotics that greatly reduced the number of deaths from infection.
How penicillin was discovered identify the problem?
Question: How did he discover penicillin? Answer: Fleming, being a bacteriologist, was searching for cures to treat bacterial infections. One day in 1928 he discovered that bacteria he had been growing on a culture plate had been killed in an area close to where a mould was accidentally growing.
How was penicillin invented?
In 1928 Dr Alexander Fleming returned from a holiday to find mould growing on a Petri dish of Staphylococcus bacteria. He noticed the mould seemed to be preventing the bacteria around it from growing. He soon identified that the mould produced a self-defence chemical that could kill bacteria.
What causes beriberi how can it be prevented?
Prevention is the best way to avoid beriberi, and it starts with eating a healthful, balanced diet. Access to fortified foods, such as bread and cereals, can significantly reduce the likelihood of a person getting beriberi.
What can Eijkman safely infer at this point from his observation?
Eijkman noticed that chickens fed a diet of white rice also suffered from a similar disorder. When the chickens were fed a diet of red rice, the chickens quickly recovered. He can infer that beriberi may be related to diet, but more and better studies are needed.
What is the disease the chickens were getting if they did not eat the right kind of rice?
The reason, he found, was their diet: When the chickens were fed on white rice alone, they came down with beriberi.
What is the strange case of beriberi?
The Strange Case of BeriBeri In 1887 a strange nerve disease attacked the people in the Dutch East Indies. The disease was beriberi. Symptoms of the disease included weakness and loss of appetite, victims often died of heart failure. Scientists thought the disease might be caused by bacteria.
What is hypothesis in research writing?
A hypothesis is a tentative statement about the relationship between two or more variables. It is a specific, testable prediction about what you expect to happen in a study.
Who is most at risk for beriberi?
Beriberi is observed in developed nations in persons with alcoholism, people on fad diets, persons on long-term peritoneal dialysis without thiamine replacement, persons undergoing long-term starvation, or persons receiving intravenous fluids with high glucose concentration.
What nutrient deficiency causes beriberi?
Thiamine deficiency, or beriberi, refers to the lack of thiamine pyrophosphate, the active form of the vitamin known as thiamine (also spelled thiamin), or vitamin B-1 (see the image below).
What happens if beriberi goes untreated?
If it goes unchecked, wet beriberi may cause injury to the heart’s muscle tissue. 1 It’s also associated with congestive heart failure, in which the heart can’t pump enough blood to meet the body’s needs. Dry beriberi injures the nerves and can lead to muscle strength loss and, eventually, paralysis.
What is a good hypothesis example?
Here’s an example of a hypothesis: If you increase the duration of light, (then) corn plants will grow more each day. The hypothesis establishes two variables, length of light exposure, and the rate of plant growth. An experiment could be designed to test whether the rate of growth depends on the duration of light.
What are 5 characteristics of a good hypothesis?
Characteristics & Qualities of a Good Hypothesis Power of Prediction. One of the valuable attribute of a good hypothesis is to predict for future. Closest to observable things. Simplicity. Clarity. Testability. Relevant to Problem. Specific. Relevant to available Techniques.
What is hypothesis example?
Examples of Hypothesis: If I replace the battery in my car, then my car will get better gas mileage. If I eat more vegetables, then I will lose weight faster. If I add fertilizer to my garden, then my plants will grow faster. If I brush my teeth every day, then I will not develop cavities.